The non-invasive monitoring of tissue engineered constructs in an environment that closely mimics in vivo conditions is one of the main challenges in regenerative medicine. In fact, the ability to visualize cells seeded on a scaffold can help elucidate cell/biomaterial interactions without sacrificing samples. In addition, monitoring the micro-environment in terms of both biochemical (i.e. the distribution of O2) and biophysical (i.e. scaffold stiffness or shear stress induced by flux) stimuli can be useful in the development of disease models as well as in the study of the cell response to drugs or toxic materials.
The NanoBioscopy Lab
The NanoBioscopy Lab, jointly run by the Research Center E. Piaggio and the Department of Biology, is dedicated to the engineeering and imaging of microenvironments for the study of physiological and disease models.