@conference {1803,
	title = {A multi-stimuli environment for cardiac tissue engineering},
	booktitle = {TERMIS 3rd World Congress},
	year = {2012},
	address = {Vienna, Austria},
	abstract = {<p>The identification of the ideal cell source to generate cardiac tissue able to integrate into the host myocardium and with the contractile system is crucial for cardiac engineering. Amongst different cell sources so far proposed, human adult Cardiac Progenitor Cells (hCPCs) show the ability to proliferate and differentiate toward cardiac lineages when grown in appropriate microenvironmental conditions. It is widely accepted that conventional 2D cultures may provide a physiological environment for growing cells. For this reason the need to have an engineered microenvironment, matching physiological requirements, is crucial. A 3D context with spatial and time varying distribution of regulatory factors using mechanically matched scaffolds and bioreactors could represent an in vitro cell culture model being able to more closely reflects the in vivo conditions. In the present study, the possibility of using biocompatible and biodegradable scaffolds of collagen based or derivatives hydrogels in combination with Linneg/Sca-1pos hCPCs gathered from human heart biopsies was investigated. Bio-constructs were placed in the low shear, high flow MCmB (MultiCompartment modular Bioreactor) and the combined effects of dynamic culture conditions and 3D scaffolds on cell morphology and differentiation were studied in order to investigate the possibility of fabricating stem cell-derived cardiac patches to replace infarcted tissue.</p>
},
	keywords = {Bioengineering, Bioreactors, Dynamic 3D Cultures},
	author = {Tirella, A and A. Ahluwalia and P. Di Nardo and Gaudiello, E and S. Giusti and F. Pagliari}
}
@article {1514,
	title = {Cooperation of Biological and Mechanical Signals in Cardiac Progenitor Cell Differentiation},
	journal = {ADVANCED MATERIALS},
	year = {2011},
	keywords = {Bioengineering},
	issn = {0935-9648},
	author = {S. Pagliari and A.C. Vilela-Silva and G. Forte and F. Pagliari and C. Mandoli and G. Vozzi and S. Pietronave and M. Prat and S. Licoccia and A. Ahluwalia and E. Traversa and M. Minieri and P. Di Nardo}
}
@inbook {1789,
	title = {{Inherently Bio-Active Scaffolds: Intelligent Constructs to Model the Stem Cell Niche}},
	booktitle = {Myocardial Tissue Engineering},
	series = {Studies in Mechanobiology, Tissue Engineering and Biomaterials},
	volume = {6},
	year = {2011},
	pages = {29{\textendash}47},
	publisher = {Springer Berlin Heidelberg},
	organization = {Springer Berlin Heidelberg},
	address = {Berlin, Heidelberg},
	abstract = {<p>The oft-abused phrase {\^a}{\texteuro}{\oe}genes load the gun, environment pulls the trigger{\^a}{\texteuro} can be applied to stem cells and stem cell niches as well as to cell{\^a}{\texteuro}{\textquotedblleft}material interfaces. Much is known about cell{\^a}{\texteuro}{\textquotedblleft}material interaction in general, perhaps a little less about how these interactions condition cell phenotype. With the increasing interest in stem cells and, in particular, their applications in tissue regeneration, the regulation of the stem cell microenvironment through modulation of intuitive or smart materials and structures, or what we term IBAS (Inherently Bio-Active Scaffolds) is poised to become a major field of research. Here, we discuss how cardiac regeneration strategies have undergone a gradual shift from the emphasis on biochemical signals and basic biology to one in which the material or scaffold plays a major role in establishing an equilibrium state. From being a constant battle or tug-of-war between the cells and synthetic environments, we conceive IBAS as intuitively responding to the cell{\^a}{\texteuro}{\texttrademark}s requirements to instate a sort of equilibrium in the system.</p>
},
	keywords = {Bioengineering},
	isbn = {978-3-642-18055-2},
	doi = {10.1007/978-3-642-18056-9},
	url = {http://www.springerlink.com/content/j3k541l113233424/},
	author = {P. Di Nardo and M. Minieri and Tirella, A and G. Forte and A. Ahluwalia},
	editor = {Boccaccini, A. R. and Harding, S. E.}
}
@conference {1528,
	title = {Resident cardiac stem cells on PAM scaffold for Heart tissue engineering application},
	booktitle = {Congress of the European Society of Biomechanics, ESB 2010},
	year = {2010},
	keywords = {Bioengineering},
	author = {M. Nardi and C. De Maria and G. Forte and P. Di Nardo and A. Ahluwalia and G. Vozzi}
}
@article {1549,
	title = {Criticality of the Biological and Physical Stimuli Array Inducing Resident Cardiac Stem Cell Determination},
	journal = {STEM CELLS},
	volume = {26},
	year = {2008},
	pages = {2093{\textendash}2103},
	keywords = {Bioengineering},
	issn = {1066-5099},
	author = {G. Forte and CAROTENUTO, F and F. Pagliari and S. Pagliari and COSSA, P and FIACCAVENTO, R and A. Ahluwalia and G. Vozzi and Vinci, B. and SERAFINO, A and RINALDI, A and E. Traversa and CAROSELLA, L and M. Minieri and P. Di Nardo}
}
@conference {1657,
	title = {Cardiac and Mesenchymal Stem Cell Growth and Selective Differentiation on Three Dimensional Bioerodable Scaffolds},
	booktitle = {Termis Eu-Meeting London (UK) 4-7 September 2007 Tissue Engineering 2007, 13 (7): 1647},
	year = {2007},
	pages = {{\textendash}},
	keywords = {Bioengineering},
	author = {G. Forte and CAROTENUTO, F and G. Vozzi and COSSA, P and FIACCAVENTO, R and M. Minieri and F. Pagliari and S. Pagliari and Romano, R. and A. Ahluwalia and E. Traversa and P. Di Nardo}
}
