%0 Conference Paper %B Gruppo Nazionale Bioingegneria IV Congresso %D 2014 %T Fluid dynamics in porous scaffolds stimulated with cyclic squeeze pressure in the S2PR bioreactor %A M. Ferroni %A S. Giusti %A G. Spatafora %A F. Boschetti %A A. Ahluwalia %K Bioengineering %X
In cardiac tissue engineering, the use of bioreactors is fundamental for applying controlled mechanical stimuli on the cells and recreate a physiological environment for cardiomyocytes cultures. This work is focused on an innovative Sensorized Squeeze PRessure (S2PR) bioreactor, able to apply a periodic contactless hydrodynamic pressures on 3D porous constructs. The fluid-dynamic environment inside the bioreactor was fully characterized using computational models, focusing on the pressures and fluid velocity profiles generated in the porous scaffold during the cyclic stimulation.
%B Gruppo Nazionale Bioingegneria IV Congresso %C Pavia, 25-27 June