TY - CONF T1 - Fluid dynamics in porous scaffolds stimulated with cyclic squeeze pressure in the S2PR bioreactor T2 - Gruppo Nazionale Bioingegneria IV Congresso Y1 - 2014 A1 - M. Ferroni A1 - S. Giusti A1 - G. Spatafora A1 - F. Boschetti A1 - A. Ahluwalia KW - Bioengineering AB -

In cardiac tissue engineering, the use of bioreactors is fundamental for applying controlled mechanical stimuli on the cells and recreate a physiological environment for cardiomyocytes cultures. This work is focused on an innovative Sensorized Squeeze PRessure (S2PR) bioreactor, able to apply a periodic contactless hydrodynamic pressures on 3D porous constructs. The fluid-dynamic environment inside the bioreactor was fully characterized using computational models, focusing on the pressures and fluid velocity profiles generated in the porous scaffold during the cyclic stimulation.

JF - Gruppo Nazionale Bioingegneria IV Congresso CY - Pavia, 25-27 June ER -