01244nas a2200169 4500008003900000245010200039210006900141260002200210520060000232653001900832100001600851700001400867700001800881700001800899700001800917856013900935 2014 d00aFluid dynamics in porous scaffolds stimulated with cyclic squeeze pressure in the S2PR bioreactor0 aFluid dynamics in porous scaffolds stimulated with cyclic squeez aPavia, 25-27 June3 a
In cardiac tissue engineering, the use of bioreactors is fundamental for applying controlled mechanical stimuli on the cells and recreate a physiological environment for cardiomyocytes cultures. This work is focused on an innovative Sensorized Squeeze PRessure (S2PR) bioreactor, able to apply a periodic contactless hydrodynamic pressures on 3D porous constructs. The fluid-dynamic environment inside the bioreactor was fully characterized using computational models, focusing on the pressures and fluid velocity profiles generated in the porous scaffold during the cyclic stimulation.
10aBioengineering1 aFerroni, M.1 aGiusti, S1 aSpatafora, G.1 aBoschetti, F.1 aAhluwalia, A. uhttp://www.centropiaggio.unipi.it/publications/fluid-dynamics-porous-scaffolds-stimulated-cyclic-squeeze-pressure-s2pr-bioreactor.html